Bayern, who won the Champions League in 2013, have yet to hit top form this season, with many players tired after the World Cup and others, including Thiago Alcantara, Bastian Schweinsteiger and Rafinha, out injured.
Klaas-Jan Huntelaar has gone on to become one of the Bundesliga's most prolific strikers since he was shunned at Real Madrid and will finally have a chance to show his former club what they are missing on Wednesday.
Football news from Ligue 1, Bundesliga and La liga.
Ahead of their high-profile clash on Saturday, check out the five standout clashes between Arsenal and Chelsea.
As Manchester United prepare to embark on a new era following Louis van Gaal;s departure, Bikash Mohapatra/Rediff.com offers a diagnosis of what went wrong with the most successful Premier League club after Sir Alex Ferguson called it a day.
Barcelona snapped a four-match winless run in La Liga with a 4-2 home victory over title rivals Sevilla on Saturday to reclaim top spot but the triumph was marred by talisman Lionel Messi fracturing his arm and being ruled out for three weeks.
Thiago Silva's extra-time header sent Paris St Germain into the Champions League quarter-finals on away goals.
A summary of sports events and sports persons, who made news on Saturday
A summary of Wednesday's matches in the UEFA Champions League.
Images from the Champions League matches played across Europe on Wednesday.
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